Bleomycin-induced flagellate hyperpigmentation

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منابع مشابه

Bleomycin‐induced flagellate hyperpigmentation

A 27-year old male with Hodgkin's lymphoma was treated with combined chemotherapy that included bleomycin. He presented with pruritic erythematous, edematous linear lesions and was diagnosed to have flagellate hyperpigmentation, a rare side effect of bleomycin chemotherapy.

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Bleomycin-induced flagellate hyperpigmentation.

Bleomycin is a chemotherapeutic agent used in the treatment of different tumours. It has several side effects, including flagellate hyperpigmentation, which is a unique and a well-documented side effect of bleomycin therapy. We report a case of a 23-year-old woman with a personal history of ovarian dysgerminoma, who developed flagellate hyperpigmentation on trunk after bleomycin therapy.

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Flagellate hyperpigmentation from bleomycin.

Sir, Mucocutaneous side effects associated with bleomycin are stomatitis, ulcers, scaly erythematous and bullous lesions, sclerosis, nail changes, digital gangrene and pigmentary alterations. Hyperpigmentation occurring mainly on the pressure areas of the skin as well as in areas of scratch marks is seen in approximately 30% of patients. Flagellate hyperpigmentation is very characteristic of bl...

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Bleomycin-induced flagellate erythema.

of bleomycin or its derivative peplomycin, occurs in 8-20% patients during systemic or local therapy (1). It characterised by a linear erythematous streak with hyperpigmentation (2, 3), and was first described by Moulin in 1970 (4). Herein, we present a typical case of flagellate erythema induced by Bleomycin. A 32 year-old Taiwanese male with mixed germ cell tumour of the anterior mediastinum ...

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Bleomycin-induced flagellate dermatitis

A 29-year-old woman with stage IVB Hodgkin's lymphoma was treated with doxorubicin, bleomycin, vinblastine, and dacarbazine. Two weeks after the first cycle was completed, she developed pruritic, linear erythematous lesions in a flagellate-like pattern on the trunk, neck and arms. After oral prednisone therapy and cessation of bleomycin, the lesions started to recede.

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ژورنال

عنوان ژورنال: Clinical Case Reports

سال: 2017

ISSN: 2050-0904

DOI: 10.1002/ccr3.831